A clinical comparative study of ofloxacin and pivampicillin in acute exacerbations of chronic bronchitis
- PMID: 3182456
- DOI: 10.1093/jac/22.supplement_c.139
A clinical comparative study of ofloxacin and pivampicillin in acute exacerbations of chronic bronchitis
Abstract
A controlled clinical study employing a double-blind, double-dummy technique was carried out on 84 patients with purulent exacerbations of chronic bronchitis. Ofloxacin (200 mg x 2 daily) and pivampicillin (700 mg x 3 daily), were compared for efficacy, safety, and adverse reactions. Both regimens had high bacteriological elimination rates (94.1, 97.2%) and clinical cure rates (97.4, 97.6%). However, there were fewer adverse reactions and a greater patient acceptance in the ofloxacin treated group.
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