Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Apr;40(4):e13.
doi: 10.1097/IAE.0000000000002710.

Correspondence

Antonello Caruso  1 , Norman A Mazer
Affiliations
Comment

Correspondence

Antonello Caruso et al. Retina. 2020 Apr.
No abstract available

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
Recalculated median concentrations versus time. Dashed line corresponds to an exponential function fit to the data, excluding the earliest time point. The decay rate of 0.072 days−1 corresponds to a half-life of 9.6 days.
See this image and copyright information in PMC

Comment in

  • Reply.
    Do DV, Rhoades W, Nguyen QD. Do DV, et al. Retina. 2020 Apr;40(4):e13-e14. doi: 10.1097/IAE.0000000000002711. Retina. 2020. PMID: 31876890 No abstract available.

Comment on

References

    1. Do DV, Rhoades W, Nguyen QD. Pharmacokinetic study of intravitreal aflibercept in humans with neovascular age-related macular degeneration. Retina 2019. Epub ahead of print. - PubMed
    1. Do DV, Nguyen QD. Pharmacokinetics of free aflibercept in patients with neovascular age related macular degeneration. Invest Ophthalmol Vis Sci 2017;58:406.
    1. Hutton-Smith LA, Gaffney EA, Byrne HM, et al. Theoretical insights into the retinal dynamics of VEGF in patients treated with ranibizumab, based on an ocular pharmacokinetic/pharmacodynamic model. Mol Pharmaceutics 2018;15:2770–2784. - PubMed

MeSH terms

Substances