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Review
. 2021 Feb;36(2):287-294.
doi: 10.1007/s00467-019-04424-2. Epub 2019 Dec 13.

Protein energy wasting; what is it and what can we do to prevent it?

Lesley Rees  1
Affiliations
Review

Protein energy wasting; what is it and what can we do to prevent it?

Lesley Rees. Pediatr Nephrol. 2021 Feb.

Abstract

Some children with declining height and BMI SDS fail to respond to optimisation of nutritional intake. As well as poor growth, they have muscle wasting and relative preservation of body fat. This is termed protein energy wasting (PEW). The process results from an interaction of chronic inflammation alongside poor nutritional intake. This review discusses the causes and potential preventative therapies for PEW.

Keywords: Cachexia; Chronic kidney disease; Protein energy wasting.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Effect of inflammation on growth hormone secretion. Reproduced from reference [23]
Fig. 2
Fig. 2
The role of fluid overload in the development of PEW
See this image and copyright information in PMC

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