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Review
. 2020 Jan:124:103528.
doi: 10.1016/j.brat.2019.103528. Epub 2019 Nov 28.

Human fear conditioning: From neuroscience to the clinic

M A Fullana  1 , J E Dunsmoor  2 , K R J Schruers  3 , H S Savage  4 , D R Bach  5 , B J Harrison  4
Affiliations
Review

Human fear conditioning: From neuroscience to the clinic

M A Fullana et al. Behav Res Ther. 2020 Jan.

Abstract

Both clinicians and neuroscientists have been long interested in the topic of fear conditioning, with recent advances in neuroscience, in particular, igniting a shared interest in further translation between these domains. Here, we review some historical aspects of this relationship and the progress that has been made in translating the neuroscientific study of fear conditioning to the conceptualization and treatment of mental disorders, especially anxiety-related disorders. We also address some conceptual and methodological challenges faced by this research, and offer some suggestions to support future progress in the field.

Keywords: Anxiety; Fear conditioning; Neuroscience.

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