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Review
. 2019 Dec 9;24(24):4506.
doi: 10.3390/molecules24244506.

The Potential Use of Resveratrol for Cancer Prevention

Dominique Vervandier-Fasseur  1 , Norbert Latruffe  2
Affiliations
Review

The Potential Use of Resveratrol for Cancer Prevention

Dominique Vervandier-Fasseur et al. Molecules. .

Abstract

In addition to the traditional treatments of cancer and cancer prevention, the use of natural compounds, especially those found in food, should be considered. To clarify if resveratrol has the potential for cancer prevention and the possibility of use in therapy, the following must be taken into account: data from epidemiology, clinical protocol (case and control), preclinical studies (lab animals), use of established cell lines as models of cancer cells, test tube assays (enzymes activities), and requirements of nanotechnologies in order to discover new drugs to fight cancer. From this perspective and future expected advances, more information is needed such as improved efficacy, methods of application, and the synergistic sensitization of resveratrol as an adjuvant. In addition, resveratrol nanoformulation is considered to overcome its weak bioavailability.

Keywords: approach strategies; cancer; innovative formulations; mechanisms; prevention; resveratrol.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Brief recall of the cell cycle phases.
Figure 2
Figure 2
Initial steps leading to cancerous cells [1] (p. 15).
Figure 3
Figure 3
Structure of trans-resveratrol RSV.
See this image and copyright information in PMC

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