Time to re-think the olanzapine dose

Affiliations

Comment

Alex Molassiotis. Lancet Oncol. 2020 Feb.

. 2020 Feb;21(2):189-190.

doi: 10.1016/S1470-2045(19)30791-0. Epub 2019 Dec 11.

¹ School of Nursing, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, China. Electronic address: alex.molasiotis@polyu.edu.hk.

No abstract available

Comment on

Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting.
Navari RM, Qin R, Ruddy KJ, Liu H, Powell SF, Bajaj M, Dietrich L, Biggs D, Lafky JM, Loprinzi CL. Navari RM, et al. N Engl J Med. 2016 Jul 14;375(2):134-42. doi: 10.1056/NEJMoa1515725. N Engl J Med. 2016. PMID: 27410922 Free PMC article. Clinical Trial.
Olanzapine 5 mg plus standard antiemetic therapy for the prevention of chemotherapy-induced nausea and vomiting (J-FORCE): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.
Hashimoto H, Abe M, Tokuyama O, Mizutani H, Uchitomi Y, Yamaguchi T, Hoshina Y, Sakata Y, Takahashi TY, Nakashima K, Nakao M, Takei D, Zenda S, Mizukami K, Iwasa S, Sakurai M, Yamamoto N, Ohe Y. Hashimoto H, et al. Lancet Oncol. 2020 Feb;21(2):242-249. doi: 10.1016/S1470-2045(19)30678-3. Epub 2019 Dec 11. Lancet Oncol. 2020. PMID: 31838011 Clinical Trial.