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Review
. 2019 Dec 17;8(24):e013225.
doi: 10.1161/JAHA.119.013225. Epub 2019 Dec 16.

Diagnosis and Treatment of Heterozygous Familial Hypercholesterolemia

Mary P McGowan  1 , Seyed Hamed Hosseini Dehkordi  2 , Patrick M Moriarty  2 , P Barton Duell  3
Affiliations
Review

Diagnosis and Treatment of Heterozygous Familial Hypercholesterolemia

Mary P McGowan et al. J Am Heart Assoc. .
No abstract available

Keywords: atherosclerosis; cardiovascular events; cardiovascular intervention; cascade screening; diagnostics; genetics; heterozygous familial hypercholesterolemia.

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Figures

Figure 1
Figure 1
Severe extensor tendon xanthomas. Reprinted with permission of Dr Patrick M. Moriarty.
Figure 2
Figure 2
Diagnostic considerations by the American Heart Association.27 ApoB indicates apolipoprotein B; FH, familial hypercholesterolemia; LDL‐C, low‐density lipoprotein cholesterol; PCSK9, proprotein convertase subtulisin/kexin type 9.
Figure 3
Figure 3
Statin dosing and ACC/AHA classification of intensity. ACC indicates American College of Cardiology; AHA, American Heart Association; LDL‐C, low‐density lipoprotein cholesterol.
Figure 4
Figure 4
The diagnosis and treatment of heterozygous familial hypercholesterolemia. ASCVD indicates atherosclerotic cardiovascular disease; CV, cardiovascular; HeFH, heterozygous familial hypercholesterolemia; LDL‐C, low‐density lipoprotein cholesterol; PCSK9, proprotein convertase subtilisin/kexin 9. Figure reproduced with permission courtesy of the FH Foundation: https://thefhfoundation.org/family-screening-for-fh-and-the-use-of-genetic-testing. Accessed April 2019.
See this image and copyright information in PMC

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