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Review
. 2020 Jul;9(4):e372.
doi: 10.1002/wdev.372. Epub 2019 Dec 15.

Regulation of rhythmic behaviors by astrocytes

F Rob Jackson  1 , Samantha You  1 , Lauren B Crowe  1
Affiliations
Review

Regulation of rhythmic behaviors by astrocytes

F Rob Jackson et al. Wiley Interdiscip Rev Dev Biol. 2020 Jul.

Abstract

Glial astrocytes of vertebrates and invertebrates are important modulators of nervous system development, physiology, and behavior. In all species examined, astrocytes of the adult brain contain conserved circadian clocks, and multiple studies have shown that these glial cells participate in the regulation of circadian behavior and sleep. This short review summarizes recent work, using fruit fly (Drosophila) and mouse models, that document participation of astrocytes and their endogenous circadian clocks in the control of rhythmic behavior. This article is categorized under: Gene Expression and Transcriptional Hierarchies > Regulatory Mechanisms Nervous System Development > Flies.

Keywords: Drosophila; astrocytes; circadian behavior; glia; mouse; sleep.

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References

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