Preemptive Treatment of Herpes Simplex Virus Reactivation in Critically Ill Patients?-Not Based on Current Data

David S Y Ong^{1

2}, Olaf L Cremer³, Marc J M Bonten^{2

4}

Affiliations

¹ Department of Medical Microbiology and Infection Control, Franciscus Gasthuis & Vlietland, Rotterdam, the Netherlands.
² Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, the Netherlands.
³ Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, the Netherlands.
⁴ Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, the Netherlands.

Comment

David S Y Ong et al. JAMA Intern Med. 2020.

. 2020 Feb 1;180(2):272-273.

doi: 10.1001/jamainternmed.2019.6423.

David S Y Ong^{1

2}, Olaf L Cremer³, Marc J M Bonten^{2

4}

¹ Department of Medical Microbiology and Infection Control, Franciscus Gasthuis & Vlietland, Rotterdam, the Netherlands.
² Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, the Netherlands.
³ Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, the Netherlands.
⁴ Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, the Netherlands.

No abstract available

Comment on

Acyclovir for Mechanically Ventilated Patients With Herpes Simplex Virus Oropharyngeal Reactivation: A Randomized Clinical Trial.
Luyt CE, Forel JM, Hajage D, Jaber S, Cayot-Constantin S, Rimmelé T, Coupez E, Lu Q, Diallo MH, Penot-Ragon C, Clavel M, Schwebel C, Timsit JF, Bedos JP, Hauw-Berlemont C, Bourenne J, Mayaux J, Lefrant JY, Mira JP, Combes A, Wolff M, Chastre J, Papazian L; Preemptive Treatment for Herpesviridae Study Group, Réseau Européen de recherche en Ventilation Artificielle Network. Luyt CE, et al. JAMA Intern Med. 2020 Feb 1;180(2):263-272. doi: 10.1001/jamainternmed.2019.5713. JAMA Intern Med. 2020. PMID: 31841577 Free PMC article. Clinical Trial.