Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Dec;24(8):536-554.
doi: 10.1093/pch/pxz134. Epub 2019 Dec 9.

The screening and management of newborns at risk for low blood glucose

[Article in English, French]
Affiliations
Review

The screening and management of newborns at risk for low blood glucose

[Article in English, French]
Michael R Narvey et al. Paediatr Child Health. 2019 Dec.

Abstract

Hypoglycemia in the first hours to days after birth remains one of the most common conditions facing practitioners across Canada who care for newborns. Many cases represent normal physiologic transition to extrauterine life, but another group experiences hypoglycemia of longer duration. This statement addresses key issues for providers of neonatal care, including the definition of hypoglycemia, risk factors, screening protocols, blood glucose levels requiring intervention, and managing care for this condition. Screening, monitoring, and intervention protocols have been revised to better identify, manage, and treat infants who are at risk for persistent, recurrent, or severe hypoglycemia. The role of dextrose gels in raising glucose levels or preventing more persistent hypoglycemia, and precautions to reduce risk for recurrence after leaving hospital, are also addressed. This statement differentiates between approaches to care for hypoglycemia during the 'transitional' phase-the first 72 hours post-birth-and persistent hypoglycemia, which occurs or presents for the first time past that point.

Keywords: Dextrose gel; Hypoglycemia; Newborn; Point-of-care.

PubMed Disclaimer

References

    1. Aziz K, Dancey P; Canadian Paediatric Society, Fetus and Newborn Committee Screening guidelines for newborns at risk for low blood glucose. Paediatr Child Health 2004;9(10):723–40. - PMC - PubMed
    1. Oxford Centre for Evidence-Based Medicine. Levels of evidence and grades of recommendation https://www.cebm.net/2009/06/oxford-centre-evidence-based-medicine-level... (Accessed August 19, 2019).
    1. Cornblath M, Reisner SH. Blood glucose in the neonate and its clinical significance. N Engl J Med 1965;273(7):378–81. - PubMed
    1. Behrman RE, Kliegman R, Jenson HB.. Nelson Textbook of Pediatrics, 16th edn. Philadelphia, PA: WB Saunders, 2000:533–4.
    1. Sinclair JC. Approaches to the definition of neonatal hypoglycemia. Acta Paediatr Jpn 1997;39 (Suppl 1):S17–20. - PubMed