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Comment
. 2019 Dec 16;29(24):R1307-R1309.
doi: 10.1016/j.cub.2019.11.011.

Neuronal Cytoskeleton: Presynaptic Boutons as Hotspots for Activity-Dependent Microtubule Nucleation

Amélie Freal  1 , Casper C Hoogenraad  2
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Neuronal Cytoskeleton: Presynaptic Boutons as Hotspots for Activity-Dependent Microtubule Nucleation

Amélie Freal et al. Curr Biol. .
Free article

Abstract

Local microtubule remodeling plays a crucial role in controlling the transport of neuronal cargo. A new study reveals that excitatory en passant boutons in the axon are hotspots for activity-induced microtubule nucleation and provide tracks for interbouton vesicle trafficking.

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