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Review
. 2019 Dec 17;12(1):137.
doi: 10.1186/s13045-019-0833-3.

Nanotechnology in cancer diagnosis: progress, challenges and opportunities

Ye Zhang  1 , Maoyu Li  1   2 , Xiaomei Gao  3 , Yongheng Chen  4 , Ting Liu  5
Affiliations
Review

Nanotechnology in cancer diagnosis: progress, challenges and opportunities

Ye Zhang et al. J Hematol Oncol. .

Abstract

In the fight against cancer, early detection is a key factor for successful treatment. However, the detection of cancer in the early stage has been hindered by the intrinsic limits of conventional cancer diagnostic methods. Nanotechnology provides high sensitivity, specificity, and multiplexed measurement capacity and has therefore been investigated for the detection of extracellular cancer biomarkers and cancer cells, as well as for in vivo imaging. This review summarizes the latest developments in nanotechnology applications for cancer diagnosis. In addition, the challenges in the translation of nanotechnology-based diagnostic methods into clinical applications are discussed.

Keywords: Cancer biomarker; Cancer diagnosis; Nanoparticle.

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Figures

Fig. 1
Fig. 1
Nanotechnology improves cancer detection and diagnosis
Fig. 2
Fig. 2
Schematic illustration of nanotechnology applications in cancer diagnosis
See this image and copyright information in PMC

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