Reply to Rockey et al., "Genomics and Chlamydial Persistence In Vivo"

Deborah Dean^{1

2

3}, Noa Ziklo⁴, Naraporn Somboonna⁴, Jung Hyuk Suh⁴, Thomas Ferrin⁵

Affiliations

¹ Center for Immunobiology and Vaccine Development, University of California San Francisco Benioff Children's Hospital Oakland Research Institute, Oakland, California, USA deborah.dean@ucsf.edu.
² Department of Bioengineering, University of California Berkeley and University of California San Francisco Joint Graduate Group, Berkeley and San Francisco, California, USA.
³ Department of Medicine and Pediatrics, University of California, San Francisco, California, USA.
⁴ Center for Immunobiology and Vaccine Development, University of California San Francisco Benioff Children's Hospital Oakland Research Institute, Oakland, California, USA.
⁵ Department of Pharmaceutical Chemistry, University of California, San Francisco, California, USA.

Comment

Deborah Dean et al. mBio. 2019.

. 2019 Dec 17;10(6):e02957-19.

doi: 10.1128/mBio.02957-19.

Deborah Dean^{1

2

3}, Noa Ziklo⁴, Naraporn Somboonna⁴, Jung Hyuk Suh⁴, Thomas Ferrin⁵

¹ Center for Immunobiology and Vaccine Development, University of California San Francisco Benioff Children's Hospital Oakland Research Institute, Oakland, California, USA deborah.dean@ucsf.edu.
² Department of Bioengineering, University of California Berkeley and University of California San Francisco Joint Graduate Group, Berkeley and San Francisco, California, USA.
³ Department of Medicine and Pediatrics, University of California, San Francisco, California, USA.
⁴ Center for Immunobiology and Vaccine Development, University of California San Francisco Benioff Children's Hospital Oakland Research Institute, Oakland, California, USA.
⁵ Department of Pharmaceutical Chemistry, University of California, San Francisco, California, USA.

No abstract available

Keywords: Chlamydia trachomatis; indole; interferon gamma; sexually transmitted diseases; trpA; tryptophan synthase.

Comment on

Genomics and Chlamydial Persistence In Vivo.
Rockey DD, Suchland RJ, Carrell SJ. Rockey DD, et al. mBio. 2019 Dec 17;10(6):e02616-19. doi: 10.1128/mBio.02616-19. mBio. 2019. PMID: 31848277 Free PMC article. No abstract available.

1. Rockey DD, Suchland R, Carrell SJ. 2019. Genomics and chlamydial persistence in vivo. mBio 10:e02616-19. doi:10.1128/mBio.02616-19. - DOI - PMC - PubMed
1. Suchland RJ, Dimond ZE, Putman TE, Rockey DD. 2017. Demonstration of persistent infections and genome stability by whole-genome sequencing of repeat-positive, same-serovar Chlamydia trachomatis collected from the female genital tract. J Infect Dis 215:1657–1665. doi:10.1093/infdis/jix155. - DOI - PMC - PubMed
1. Somboonna N, Ziklo N, Ferrin TE, Hyuk Suh J, Dean D. 2019. Clinical persistence of Chlamydia trachomatis sexually transmitted strains involves novel mutations in the functional αββα tetramer of the tryptophan synthase operon. mBio 10:e01464-19. - PMC - PubMed
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