Editorial: Emerging Therapeutic Approaches for Cystic Fibrosis

Miquéias Lopes-Pacheco¹, Nicoletta Pedemonte², Anthony Kicic^{3

4

5

6}

Affiliations

¹ Biosystems & Integrative Sciences Institute (BioISI), Faculty of Sciences, University of Lisbon, Lisbon, Portugal.
² UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, Genova, Italy.
³ Telethon Kids Institute, University of Western Australia, Nedlands, WA, Australia.
⁴ Occupation and Environment, School of Public Health, Curtin University, Bentley, WA, Australia.
⁵ Department of Respiratory Medicine, Princess Margaret Hospital for Children, Perth, WA, Australia.
⁶ Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, The University of Western Australia and Harry Perkins Institute of Medical Research, Nedlands, WA, Australia.

PMID: 31849681
PMCID: PMC6895245
DOI: 10.3389/fphar.2019.01440

Editorial

Editorial: Emerging Therapeutic Approaches for Cystic Fibrosis

Miquéias Lopes-Pacheco et al. Front Pharmacol. 2019.

. 2019 Nov 29:10:1440.

doi: 10.3389/fphar.2019.01440. eCollection 2019.

Authors

Miquéias Lopes-Pacheco¹, Nicoletta Pedemonte², Anthony Kicic^{3

4

5

6}

Affiliations

¹ Biosystems & Integrative Sciences Institute (BioISI), Faculty of Sciences, University of Lisbon, Lisbon, Portugal.
² UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, Genova, Italy.
³ Telethon Kids Institute, University of Western Australia, Nedlands, WA, Australia.
⁴ Occupation and Environment, School of Public Health, Curtin University, Bentley, WA, Australia.
⁵ Department of Respiratory Medicine, Princess Margaret Hospital for Children, Perth, WA, Australia.
⁶ Centre for Cell Therapy and Regenerative Medicine, School of Medicine and Pharmacology, The University of Western Australia and Harry Perkins Institute of Medical Research, Nedlands, WA, Australia.

PMID: 31849681
PMCID: PMC6895245
DOI: 10.3389/fphar.2019.01440

No abstract available

Keywords: cystic fibrosis transmembrane conductance regulator; drug development; infection; inflammation; lung; modulators; mutations; therapeutic approach.

PubMed Disclaimer

Comment on

Editorial on the Research Topic Emerging Therapeutic Approaches for Cystic Fibrosis

References

1. Keating D., Marigowda G., Burr L., Daines C., Mall M. A., NcKone E. F., et al. (2018). VX-445-tezacaftor-ivacaftor in patients with cystic fibrosis and one or two phe508del alleles. N. Engl. J. Med. 379 (17), 1612–1620. 10.1056/NEJMoa1807120 - DOI - PMC - PubMed
1. Kerem B., Rommens J. M., Buchanan J. A., Markiewicz D., Cox T. K., Chakravarti A., et al. (1989). Identification of the cystic fibrosis gene: genetic analysis. Science 245 (4922), 1073–1080. 10.1126/science.2570460 - DOI - PubMed
1. Lopes-Pacheco M. (2016). CFTR modulators: shedding light on precision medicine for cystic fibrosis. Front. Pharmacol. 7, 275. 10.3389/fphar.2016.00275 - DOI - PMC - PubMed
1. Ramsey B. W., Davies J., McElvaney N. G., Tullis E., Bell S. C., Drevínek P., et al. (2011). A CFTR potentiator in patients with cystic fibrosis and the G551D mutation. N. Engl. J. Med. 365 (18), 1663–1672. 10.1056/NEJMoa1105185 - DOI - PMC - PubMed
1. Riordan J. R., Rommens J. M., Kerem B., Alon N., Rozmahel R., Grzelczak Z., et al. (1989). Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245 (4922), 1066–1073. 10.1126/science.2475911 - DOI - PubMed

Publication types

Actions

LinkOut - more resources

Full Text Sources

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Editorial: Emerging Therapeutic Approaches for Cystic Fibrosis

Affiliations

Editorial: Emerging Therapeutic Approaches for Cystic Fibrosis

Authors

Affiliations

Comment on

References

Publication types

LinkOut - more resources

Full Text Sources