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Review
. 2020 Jul;9(4):e370.
doi: 10.1002/wdev.370. Epub 2019 Dec 18.

Neuronal diversity and reciprocal connectivity between the vertebrate hippocampus and septum

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Review

Neuronal diversity and reciprocal connectivity between the vertebrate hippocampus and septum

Archana Iyer et al. Wiley Interdiscip Rev Dev Biol. 2020 Jul.

Abstract

A hallmark of the nervous system is the precision with which myriad cell types are integrated into functional networks that control complex behaviors. The limbic system governs evolutionarily conserved processes essential for survival. The septum and the hippocampus are central to the limbic system, and control not only emotion-related behaviors but also learning and memory. Here, we provide a developmental and evolutionary perspective of the hippocampus and septum and highlight the neuronal diversity and circuitry that connects these two central components of the limbic system. This article is categorized under: Nervous System Development > Vertebrates: Regional Development Nervous System Development > Vertebrates: General Principles Comparative Development and Evolution > Regulation of Organ Diversity.

Keywords: hippocampus; neuronal diversity; septum.

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References

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