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Case Reports
. 2019 Dec 11:12:1179550619886561.
doi: 10.1177/1179550619886561. eCollection 2019.

Pleomorphic Adenoma of the Ala Nasi: A Case Report

Amina Mouzali  1 , Samia Lameche  2 , Assia Slimani  2 , Omar Zemirli  1
Affiliations
Case Reports

Pleomorphic Adenoma of the Ala Nasi: A Case Report

Amina Mouzali et al. Clin Med Insights Ear Nose Throat. .

Abstract

Objectives: Pleomorphic adenomas are benign tumors that rarely involve nonsalivary glands. We report an uncommon case of ala nasi pleomorphic adenoma. We discuss the clinical and histopathologic characteristics, and review the literature on nasal pleomorphic adenoma.

Method: A 20-year-old man presented with a painless slow growing lobulated mass located on the right ala nasi extending into the nasal vestibule.

Results: Complete surgical excision was performed. Histologic examination found a mixed cellular component: epithelial and myoepithelial cells with chondromyxoid stroma. This was consistent with the diagnosis of a typical pleomorphic adenoma. There was no evidence of recurrence at 18 months after the surgery.

Conclusions: Pleomorphic adenomas located in the external nose are extremely rare. In such case, pleomorphic adenoma could originate from ectopic minor salivary gland. Complete surgical excision with long-term follow-up is recommended due to the potential risk of recurrence and malignant transformation.

Keywords: Pleomorhpic adenoma; ala nasi; nose; tumor.

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Conflict of interest statement

Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Lobulated mass located on the right ala nasi, of approximately 2 cm × 1 cm in size, covered by adherent and thinned skin.
Figure 2.
Figure 2.
Endonasal view of a nonobstructive mass covered by a normal vestibular skin.
Figure 3.
Figure 3.
Intraoperative view: complete tumor dissection removing adherent skin (blue arrow) via intranasal vestibular incision.
Figure 4.
Figure 4.
Histopathologic photomicrograph showing epithelial and myoepithlial cells in myxoid stromal component (H&E; x200). Blue arrow indicates fibrous capsule; red arrow, mesenchymatous component; yellow arrow, epithelial and myoepithelial component.
Figure 5.
Figure 5.
Immunohistochemistry photomicrograph revealing myoepithelial cells with positive cytokeratin 7 expression (red arrow) (H&E; x400).
See this image and copyright information in PMC

References

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