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. 2020 Jun;24(6):1929-1941.
doi: 10.1007/s10461-019-02763-7.

Use of Rapid HIV Self-Test to Screen Potential Sexual Partners: Results of the ISUM Study

Alex Carballo-Diéguez  1 , Rebecca Giguere  2 , Iván C Balán  2 , William Brown 3rd  2   3   4   5 , Curtis Dolezal  2 , Cheng-Shiun Leu  2   6 , Javier Lopez Rios  2   7 , Alan Z Sheinfil  8 , Timothy Frasca  2 , Christine Tagliaferri Rael  2 , Cody Lentz  2 , Raynier Crespo  9 , Sarah Iribarren  10 , Catherine Cruz Torres  9 , Irma Febo  9
Affiliations

Use of Rapid HIV Self-Test to Screen Potential Sexual Partners: Results of the ISUM Study

Alex Carballo-Diéguez et al. AIDS Behav. 2020 Jun.

Abstract
in English, Spanish

ISUM ("I'll show you mine") was a randomized controlled trial in which 272 transgender women and men who have sex with men in New York, NY (NYC) and San Juan, Puerto Rico (SJU) were assigned to an intervention group (n = 136), in which they had access to free HIV self-testing (ST) kits, or to a control group (n = 136). The trial aimed to determine whether the intervention group would use ST to screen sexual partners and have fewer condomless anal intercourse (CAI) occasions with serodiscordant or unknown status partners than the control group. The intervention group had on average 10 (32%) fewer CAI occasions; though clinically relevant, this difference fell short of statistical significance (p = .08). In NYC (n = 166) intervention participants had significantly fewer CAI occasions, whereas in SJU (n = 106) they reported non-significantly more CAI occasions. Two devastating hurricanes hit SJU during the study and may have impacted results in unmeasured ways.

Te lo (“Te lo enseño”) fue un ensayo aleatorio controlado en el cual 272 mujeres transgénero y hombres que tienen sexo con hombres en la ciudad de Nueva York (NYC) y San Juan, Puerto Rico (SJU) fueron asignados a un grupo de la intervención (n=136), en el cual fueron provistos del autotest de VIH (ST) gratis, o a un grupo de control (n=136). El ensayo fue diseñado para determinar si los participantes del grupo de intervención usarían ST para testear a parejas sexuales potenciales y tendrían menos ocasiones de sexo anal sin condones (CAI) con parejas serodiscordantes o con un estatus desconocido comparados con los participantes en el grupo de control. El grupo de la intervención tuvo como promedio 10 (32%) ocasiones menos de CAI que el grupo de control; sin embargo, esta diferencia no tuvo significancia estadística. En NYC (n=166) los participantes del grupo de la intervención tuvieron significativamente menos ocasiones de CAI que el grupo de control, mientras que en SJU (n=106), reportaron un número de ocasiones de CAI mayor, aunque la diferencia no tuvo significación estadística. Dos huracanes devastadores afectaron a SJU durante el estudio y esto pudo haber impactado los resultados de la intervención de maneras no medidas.

Keywords: HIV; MSM; Prevention; Self-testing; Transgender women.

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Figures

Fig 1.
Fig 1.. Study design
Fig 1.
Fig 1.. Study design
Fig 2.
Fig 2.. SMS-CASI micro-questionnaire tree
Note: AS = anal sex, C = condoms. Participants had been trained on the meaning of these abbreviations.
Fig 3.
Fig 3.
See this image and copyright information in PMC

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