Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 May;14(3):691-692.
doi: 10.1177/1932296819895541. Epub 2019 Dec 19.

A Novel Approach for the Assessment of Insulin Potency by Glycemic Monitoring of an Insulin-Dependent Human Cell Line

Sven Delbeck  1 , Adrian Krolinski  1 , Yannick Dederich  1 , Sandra Stoppelkamp  1 , Herbert Michael Heise  1
Affiliations

A Novel Approach for the Assessment of Insulin Potency by Glycemic Monitoring of an Insulin-Dependent Human Cell Line

Sven Delbeck et al. J Diabetes Sci Technol. 2020 May.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Glucose (a) and lactate (b) concentration results, calculated by multivariate analysis of the dialysate infrared spectra. In both trials, the monocyte cells have been grown in a culture medium containing US pharmacopoeia human insulin.
See this image and copyright information in PMC

References

    1. Beals JM, DeFilippis MR, Kovach PM, Jackson JA. Insulin. In: Crommelin DJA, Sindelar RD, Meibohm B, eds. Pharmaceutical Biotechnology. 4th ed. New York, NY: Springer; 2013:255-275.
    1. Hamza AA. Biological assay of insulin: an old problem re-discovered. J Adv Tech Endo Res. 2018;1(1):180002.
    1. Goodman Snitkoff G. Biological testing. In: Troy DB, ed. Remington – The Science and Practice of Pharmacy. 21st ed Philadelphia: Lippincot Williams & Wilkins; 2006:553-564.
    1. USP – US Pharmacopoeia. Chapter <121> Insulin Assays. 2015. https://www.uspnf.com/sites/default/files/usp_pdf/EN/USPNF/gc_121_insuli.... Accessed December 9, 2019.
    1. Hack R, Rueggeberg S, Schneider L, Mayert D, Tennagels N, Welte S. Progress towards the replacement of the rabbit blood sugar bioidentity assay by an in vitro test for batch release of insulins in quality control. ALTEX. 2017;34(4):565-567. - PubMed