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. 2019 Dec 19;14(12):e0226750.
doi: 10.1371/journal.pone.0226750. eCollection 2019.

Healthcare utilization and costs of cardiopulmonary complications following cardiac surgery in the United States

Affiliations

Healthcare utilization and costs of cardiopulmonary complications following cardiac surgery in the United States

Mitali Stevens et al. PLoS One. .

Abstract

Purpose: This study examined postoperative heart failure (HF) and respiratory failure (RF) complications and related healthcare utilization for one year following cardiac surgery.

Methods: This study identified adult patients undergoing isolated coronary artery bypass graft (CABG) and/or valve procedures from the Cerner Health Facts® database. It included patients experiencing postoperative HF or RF complications. We quantified healthcare utilization using the frequency of inpatient admissions, emergency department (ED) visits with or without hospital admission, and outpatient visits. We then determined direct hospital costs from the determined healthcare utilization. We analyzed trends over time for both HF and RF and evaluated the association between surgery type and HF complication.

Results: Of 10,298 patients with HF complications, 1,714 patients (16.6%) developed persistent HF; of the 10,385 RF patients, 175 (1.7%) developed persistent RF. Healthcare utilization for those with persistent complications over the one-year period following index hospital discharge comprised an average number of the following visit types: Inpatient (1.49 HF; 1.55 RF), Outpatient (2.02, 0.51), ED without hospital admission (0.33, 0.13), ED + Inpatient (0.08, 0.06). Per patient annual costs related to persistent complications of HF and RF were $20,857 and $30,745, respectively. There was a significant association between cardiac surgical type and the incidence of HF, with risk for isolated valve procedures (adjusted OR 2.60; 95% CI: 2.35-2.88) and CABG + valve procedures (adjusted OR 2.38; 95% CI: 2.17-2.61) exceeding risk for isolated CABG procedures.

Conclusions: This study demonstrates that HF and RF complication rates post cardiac surgery are substantial, and complication-related healthcare utilization over the first year following surgery results in significant incremental costs. Given the need for both payers and providers to focus on healthcare cost reduction, this study fills an important gap in quantifying the mid-term economic impact of postoperative cardiac surgical complications.

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Conflict of interest statement

This work was supported financially by Edwards Lifesciences. MS is an employee of Edwards Lifesciences. ADS works as a consultant for Edwards Lifesciences. SHM works as a consultant and AVS, BLAG, XZ, and HOY as employees, for Boston Strategic Partners, Inc., who received funds from Edwards Lifesciences to perform the research. This does not alter our adherence to PLOS ONE policies on sharing data and materials. The data that support the findings of this study are available as the Cerner Health Facts® database from the Cerner Corporation, which is available to the public through licensure with Cerner Corporation.

Figures

Fig 1
Fig 1. Patient selection and flow diagram.
Fig 2
Fig 2
Rates* of heart failure (HF) and respiratory failure (RF) for the index visit by a) surgical year (2011–2016); b) surgical type (CABG, Valve, CABG + Valve). A) There was a significant difference in the rate of HF and RF over time (p<0.0001 for each); B) There was a significant association between surgical type (isolated CABG, isolated valve, or CABG + valve) and complication rates for HF or RF (p<0.001 for each complication). *All rates are expressed as percentages of each category.
Fig 3
Fig 3. Heart failure- and respiratory failure-related healthcare utilization in the one-year post surgery.
Healthcare utilization over the one-year period following index hospital discharge comprised an average number of the following visit types: Inpatient (1.49 HF; 1.55 RF), Outpatient (2.02, 0.51), Emergency Department (0.33, 0.13), Emergency Department + Inpatient (0.08, 0.06).

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