Chimeric Antigen Receptor T-Cells and Cardiovascular Toxicity: Cause for Concern?

Affiliations

¹ Department of Cardiology, Groupe Interdisciplinaire de Genoproteomique Appliquee Cardiovascular Sciences, University of Liège, Liège, Belgium; Gruppo Villa Maria Care and Research, Anthea Hospital, Bari, Italy. Electronic address: plancellotti@chuliege.be.
² Department of Cardiology, Groupe Interdisciplinaire de Genoproteomique Appliquee Cardiovascular Sciences, University of Liège, Liège, Belgium.
³ Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy.

Free article

Editorial

Patrizio Lancellotti et al. J Am Coll Cardiol. 2019.

Free article

. 2019 Dec 24;74(25):3109-3111.

doi: 10.1016/j.jacc.2019.10.028.

¹ Department of Cardiology, Groupe Interdisciplinaire de Genoproteomique Appliquee Cardiovascular Sciences, University of Liège, Liège, Belgium; Gruppo Villa Maria Care and Research, Anthea Hospital, Bari, Italy. Electronic address: plancellotti@chuliege.be.
² Department of Cardiology, Groupe Interdisciplinaire de Genoproteomique Appliquee Cardiovascular Sciences, University of Liège, Liège, Belgium.
³ Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy.

No abstract available

Keywords: CAR-T cell therapy; cardiovascular toxicity; cell therapy; checkpoint inhibition; immunotherapy.

Comment on

Cardiovascular Events Among Adults Treated With Chimeric Antigen Receptor T-Cells (CAR-T).
Alvi RM, Frigault MJ, Fradley MG, Jain MD, Mahmood SS, Awadalla M, Lee DH, Zlotoff DA, Zhang L, Drobni ZD, Hassan MZO, Bassily E, Rhea I, Ismail-Khan R, Mulligan CP, Banerji D, Lazaryan A, Shah BD, Rokicki A, Raje N, Chavez JC, Abramson J, Locke FL, Neilan TG. Alvi RM, et al. J Am Coll Cardiol. 2019 Dec 24;74(25):3099-3108. doi: 10.1016/j.jacc.2019.10.038. J Am Coll Cardiol. 2019. PMID: 31856966 Free PMC article.