Mitochondrial DNA promotes autoimmunity

Affiliations

Comment

Mary K Crow. Science. 2019.

. 2019 Dec 20;366(6472):1445-1446.

doi: 10.1126/science.aaz9308.

¹ Mary Kirkland Center for Lupus Research, Hospital for Special Surgery, New York, NY 10021, USA. crowm@hss.edu.

No abstract available

Comment on

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease.
Kim J, Gupta R, Blanco LP, Yang S, Shteinfer-Kuzmine A, Wang K, Zhu J, Yoon HE, Wang X, Kerkhofs M, Kang H, Brown AL, Park SJ, Xu X, Zandee van Rilland E, Kim MK, Cohen JI, Kaplan MJ, Shoshan-Barmatz V, Chung JH. Kim J, et al. Science. 2019 Dec 20;366(6472):1531-1536. doi: 10.1126/science.aav4011. Epub 2019 Dec 19. Science. 2019. PMID: 31857488 Free PMC article.