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Review
. 2020 Apr;41(4):789-793.
doi: 10.1007/s10072-019-04189-4. Epub 2019 Dec 19.

An "all-wheel drive" proposal to accelerate clinical research in common and rare neurological diseases

Marco Salvetti  1   2 , Mario A Battaglia  3   4 , Massimiliano Di Filippo  5 , Gian Luigi Mancardi  6 , Michelangelo Mancuso  7 , Francesco Patti  8 , Maria Pia Sormani  9 , Paola Zaratin  10
Affiliations
Review

An "all-wheel drive" proposal to accelerate clinical research in common and rare neurological diseases

Marco Salvetti et al. Neurol Sci. 2020 Apr.

Abstract

The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases.

Keywords: Clinical research; Multiple sclerosis; Pathophysiology; Rare diseases; Therapies.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

References

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