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Multicenter Study
. 2020 Feb;23(2):240-246.
doi: 10.1111/1756-185X.13771. Epub 2019 Dec 19.

Predictive factors for work-day loss in Behçet's syndrome: A multi-center study

Gonca Mumcu  1 , Meral Yay  2 , Aysun Aksoy  3 , Mehmet Nedim Taş  4 , Berkan Armağan  5 , Alper Sarı  5 , Burçin Cansu Bozca  6 , Emre Tekgöz  7 , Duygu Temiz Karadağ  8 , Suade Özlem Badak  9 , Duygu Tecer  10 , Cemal Bes  11 , Ali Şahin  12 , Eren Erken  9 , Ayse Cefle  8 , Muhammet Çınar  7 , Sedat Yılmaz  7 , Ümit Karaçaylı  13 , Erkan Alpsoy  6 , Soner Şenel  14 , Şule Yaşar Bilge  15 , Timuçin Kaşifoğlu  15 , Ömer Karadağ  5 , Kenan Aksu  4 , Gökhan Keser  4 , Fatma Alibaz-Öner  3 , Nevsun İnanç  3 , Tülin Ergun  16 , Haner Direskeneli  3
Affiliations
Multicenter Study

Predictive factors for work-day loss in Behçet's syndrome: A multi-center study

Gonca Mumcu et al. Int J Rheum Dis. 2020 Feb.

Abstract

Objective: The aim of this multi-center study was to assess predictive factors for work-day loss as an indirect cost element in Behçet's syndrome (BS).

Methods: In this cross-sectional, multi-center study, 834 BS patients (F/M: 441/393, age mean: 38.4 ± 10.9 years) were included. Data were collected by a questionnaire regarding treatment protocols, disease duration, smoking pattern, frequency of medical visits during the previous year and self-reported work-day loss during the previous year.

Results: Work-day loss was observed in 16.2% of patients (M/F: 103/32). The percentages of being a smoker (81.8%), using immunosuppressive (IS) medications (82%), and having disease duration <5 years (74%) were higher in male patients with work-day loss (P < .05). The majority of males (90.9%) had more than four clinic visits during the previous year. Moreover, the mean work-day loss (30.8 ± 57.7 days) was higher in patients with vascular involvement (56.1 ± 85.9) than those without (26.4 ± 50.6 days) (P = .046). In addition, increased frequency of ocular involvement (25.9%) was also observed in patients with work-day loss compared to others (8.6%) (P = .059).

Conclusion: Work-day loss was associated with both vascular and ocular involvement. Close associations were observed among male gender, early period of the disease, frequent medical visits, being a smoker and treatment with IS medications in patients with work-day loss.

Keywords: Behçet's disease; ocular involvement; vascular involvement; work-day loss.

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References

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