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. 2019 Dec 20:53:e20180498.
doi: 10.1590/0037-8682-0498-2018. eCollection 2019.

Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption

Ághata Cardoso da Silva Ribeiro  1 , Márcia Terezinha Lonardoni Crozatti  1 , Adilson Aderito da Silva  2 , Rodrigo Spineli Macedo  3 , Antonia Maria de Oliveira Machado  4 , Antonio Távora de Albuquerque Silva  1
Affiliations

Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption

Ághata Cardoso da Silva Ribeiro et al. Rev Soc Bras Med Trop. .

Abstract

Introduction: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance.

Methods: Data were obtained from ICUs between 2010 and 2013.

Results: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem, meropenem, and polymyxin B.

Conclusions: Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multi-drug resistance.

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Conflict of interest statement

Conflict of Interest: The authors declare that there are no conflicts of interest.

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