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. 2019 Dec 20;9(1):19547.
doi: 10.1038/s41598-019-56095-6.

Treatment evaluation to improve preventing mother to child transmission among women with syphilis

Tian Gong  1 , Yan Shao  2 , Juning Liu  2 , Qianlan Wu  2 , Rong Xu  2 , Li Sun  2 , Xiaoju Peng  2
Affiliations

Treatment evaluation to improve preventing mother to child transmission among women with syphilis

Tian Gong et al. Sci Rep. .

Abstract

The aim of this study was to evaluate the effectiveness of preventing mother to child syphilis transmission to improve pregnancy outcomes. We performed a retrospective analysis of municipal databases of mother-to-child syphilis transmission. Pregnant women with syphilis were included. Group specific pregnancy outcomes were analyzed according to treatment. A total of 28 pregnant women were diagnosed with syphilis in 2012; 321 were diagnosed with syphilis in 2018. A prevalence of 0.14% was observed amongst pregnant women in Suzhou city from 2012-2018. Primary treatments included benzathine penicillin, ceftriaxone sodium or erythromycin when patients were allergic to Benzathine penicillin. The treatment coverage was 81.57%, and only 52.86% of pregnant women were adequately treated. Adverse pregnant outcomes were higher amongst untreated women. Expanding early screening coverage and promoting treatment were key to improving pregnancy outcomes amongst women with syphilis.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Treatment rates of pregnant women and newborns. (p ≤ 0.05 was considered statistically significant.
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