Multifaceted roles of COPII subunits in autophagy
- PMID: 31863790
- DOI: 10.1016/j.bbamcr.2019.118627
Multifaceted roles of COPII subunits in autophagy
Abstract
COPII vesicles mediate anterograde ER-Golgi traffic of newly synthesized proteins in nutrient rich conditions. An accumulating body of results indicates that the secretory COPII vesicles can be shifted to the roles in autophagosome formation and selective ER-phagy (autophagy of ER), depending on their specific subunits, in response to environmental stresses. In this mini-review, we summarize and discuss the multifaceted roles of COPII vesicles in autophagy and the underlying molecular mechanisms.
Keywords: Autophagy; COPII; ER-Golgi traffic; ER-phagy.
Copyright © 2019 Elsevier B.V. All rights reserved.
Conflict of interest statement
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Similar articles
-
New insights into the structural mechanisms of the COPII coat.Traffic. 2010 Mar;11(3):303-10. doi: 10.1111/j.1600-0854.2009.01026.x. Epub 2009 Dec 7. Traffic. 2010. PMID: 20070605 Review.
-
COPII vesicles in plant autophagy and endomembrane trafficking.FEBS Lett. 2022 Sep;596(17):2314-2323. doi: 10.1002/1873-3468.14362. Epub 2022 May 11. FEBS Lett. 2022. PMID: 35486434 Review.
-
COPII and COPI traffic at the ER-Golgi interface.Physiology (Bethesda). 2011 Oct;26(5):348-64. doi: 10.1152/physiol.00017.2011. Physiology (Bethesda). 2011. PMID: 22013193 Review.
-
A unique AtSar1D-AtRabD2a nexus modulates autophagosome biogenesis in Arabidopsis thaliana.Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2021293118. doi: 10.1073/pnas.2021293118. Proc Natl Acad Sci U S A. 2021. PMID: 33879613 Free PMC article.
-
COPII collar defines the boundary between ER and ER exit site and does not coat cargo containers.J Cell Biol. 2021 Jun 7;220(6):e201907224. doi: 10.1083/jcb.201907224. J Cell Biol. 2021. PMID: 33852719 Free PMC article.
Cited by
-
ER exit in physiology and disease.Front Mol Biosci. 2024 Jan 18;11:1352970. doi: 10.3389/fmolb.2024.1352970. eCollection 2024. Front Mol Biosci. 2024. PMID: 38314136 Free PMC article. Review.
-
The IRE1α pathway in glomerular diseases: The unfolded protein response and beyond.Front Mol Med. 2022 Sep 26;2:971247. doi: 10.3389/fmmed.2022.971247. eCollection 2022. Front Mol Med. 2022. PMID: 39086958 Free PMC article. Review.
-
Spatial proteomics reveals secretory pathway disturbances caused by neuropathy-associated TECPR2.Nat Commun. 2023 Feb 16;14(1):870. doi: 10.1038/s41467-023-36553-6. Nat Commun. 2023. PMID: 36797266 Free PMC article.
-
Specific microRNAs for Modulation of Autophagy in Spinal Cord Injury.Brain Sci. 2022 Feb 11;12(2):247. doi: 10.3390/brainsci12020247. Brain Sci. 2022. PMID: 35204010 Free PMC article. Review.
-
COPII cage assembly factor Sec13 integrates information flow regulating endomembrane function in response to human variation.Sci Rep. 2024 May 3;14(1):10160. doi: 10.1038/s41598-024-60687-2. Sci Rep. 2024. PMID: 38698045 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
