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Review
. 2019 Dec 20;92(4):751-755.
eCollection 2019 Dec.

Brain Death Criteria: Medical Dogma and Outliers

Affiliations
Review

Brain Death Criteria: Medical Dogma and Outliers

Molly Rayner et al. Yale J Biol Med. .

Abstract

The diagnosis of brain death (BD) is legally and medically accepted. Recently, several high-profile cases have led to discussions regarding the integrity of current criteria, and many physiologic problems have been identified to support the necessity for their reevaluation. These include a global variability of the criteria, the suggestion of a clinical "hierarchy," and the resultant approximation of BD. Further ambiguity has been exposed through case reports of reversible BD, and an inconsistent understanding from physicians who are viewed as experts in this domain. Meeting BD criteria clearly does not equate to a physiologic "death" of the brain, and a greater community perspective should be considered as the dialogue moves forward.

Keywords: brain death; determination of death.

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References

    1. Madoff RD. Immortality and the law: the rising power of the American dead. Yale University Press; 2010. pp. 1–11.
    1. Nakagawa TA, Ashwal SA, Mathur M, Mysore M, Committee for Determination of Brain Death in Infants Children Guidelines for the determination of brain death in infants and children: an update of the 1987 Task Force recommendations – executive summary. Ann Neurol. 2012;71(4):573–85. - PubMed
    1. Wijdicks EF, Panayiotis NV, Gronseth GS, Greer DM. Evidence-based guideline update: determining brain death in adults. Neurology. 2010;74(23):1911–8. - PubMed
    1. Pope T. Brain death and the law: hard cases and legal challenges. Hastings Cent Rep. 2018;48(6):S46–8. - PubMed
    1. Lewis A, Pope TM. Physician power to declare death by neurologic criteria threatened. Neurocrit Care. 2017;26(3):446–9. - PubMed

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