Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Dec 3:27:1-3.
doi: 10.1016/j.mmcr.2019.12.002. eCollection 2020 Mar.

Cryptococcus gattii infection in an immunocompetent host in Greece

Marina Andreou  1 , Massimo Cogliati  2 , Fevronia Kolonitsiou  3 , Charalampos Stroumpos  4 , Vasiliki Stamouli  3 , Panagiota Ravazoula  5 , Dimitrios Siagris  1 , Helen Papadogeorgaki  6 , Myrto Christofidou  3 , Alexandra Lekkou  7
Affiliations
Case Reports

Cryptococcus gattii infection in an immunocompetent host in Greece

Marina Andreou et al. Med Mycol Case Rep. .

Abstract

We report a case of a 31-year-old otherwise healthy female with pulmonary cryptococcoma along with cryptococcal meningitis due to Cryptococcus gattii molecular type VGI, in Greece. Combined antifungal treatment and surgical excision of pulmonary cryptococcoma yielded a good response.

Keywords: Cryptococcal meningitis; Cryptococcosis; Cryptococcus gattii; Greece; Pulmonary cryptococcoma.

PubMed Disclaimer

Conflict of interest statement

There are none.

Figures

Fig. 1
Fig. 1
Magnetic resonance imaging: Multiple cryptococcoma lesions in the cerebellar hemisperes, the internal capsule and the left hypothalamic nucleus (arrows). After the administration of paramagnetic drug, meningeal enhancement was detected.
Fig. 2
Fig. 2
Pulmonary cryptococcoma: A well circumscribed mass of the left inferior lung lobe.
Fig. 3
Fig. 3
a Mayer's mucicarmine stain of lung tissue: encapsulated yeasts of Cryptococcus spp. presenting carminophilic capsule are intensely stained with magenta color by mucicarmine. b Grocott's methenamine silver stain: fungal cells stained in black.. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
See this image and copyright information in PMC

References

    1. Kwon-Chung K.J., Bennett J.E., Wickes B.L., Meyer W., Cuomo C.A., Wollenburg K.R. The case for adopting the “species complex” nomenclature for the etiologic agents of cryptococcosis. mSphere. 2017;2(1) - PMC - PubMed
    1. Hagen F., Khayhan K., Theelen B., Kolecka A., Polacheck I., Sionov E. Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex. Fungal Genet. Biol. 2015;78:16–48. - PubMed
    1. Chen S.C.-A., Slavin M.A., Heath C.H., Geoffrey Playford E., Byth K., Marriott D. Clinical manifestations of cryptococcus gattii infection: determinants of neurological sequelae and death. Clin. Infect. Dis. 2012;55(6):789–798. - PubMed
    1. MacDougall L., Fyfe M., Romney M., Starr M., Galanis E. Risk factors for Cryptococcus gattii infection, British Columbia, Canada. Emerg. Infect. Dis. 2011;17(2):193–199. - PMC - PubMed
    1. Hagen F., Colom M.F., Swinne D., Tintelnot K., Iatta R., Montagna M.T. Autochthonous and dormant Cryptococcus gattii infections in Europe. Emerg. Infect. Dis. 2012;18(10):1618–1624. - PMC - PubMed

Publication types