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Review
. 2020 May;40(5):552-566.
doi: 10.1002/jat.3931. Epub 2019 Dec 22.

Environmental exposure of arsenic and fluoride and their combined toxicity: A recent update

Paritosh Mondal  1 , Ansuman Chattopadhyay  1
Affiliations
Review

Environmental exposure of arsenic and fluoride and their combined toxicity: A recent update

Paritosh Mondal et al. J Appl Toxicol. 2020 May.

Abstract

Environmental exposure to arsenic (As) and fluoride (F) in the recent year has been increased because of excessive use of naturally contaminated ground water. Surface water is also regularly contaminated with these elements in various industrial areas. Arsenicosis and fluorosis upon individual exposure of As and F are reported in many studies. A syndrome of endemic As poisoning and fluorosis occurs during concurrent exposure of As and F. Previous reports showed synergistic, antagonistic and independent effects of these two compounds, although few recent reports also revealed antagonistic effects after co-exposure. Interaction during intestinal absorption and influence of F on As metabolism might be the cause of antagonism. The synergism/antagonism is thought to depend on the dose and duration of the co-exposure. However, the detailed mechanism is still not fully understood and needs further studies. Removal technologies of As and F from contaminated water is available but removal of such contaminants from food is yet to be developed. Antioxidants are useful to mitigate the toxic effects of As and F. This review focused on the effect of co-exposure, amelioration as well as removal techniques of As and F.

Keywords: amelioration; arsenic; co-exposure; fluoride; mixture effect; removal technology.

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References

REFERENCES

    1. Ahmadi, B., & Moradkhani, H. (2019). Revisiting hydrological drought propagation and recovery considering water quantity and quality. Hydrological Processes, 33(10), 1492-1505. https://doi.org/10.1002/hyp.13417
    1. Alarcón-Herrera, M. T., Bundschuh, J., Nath, B., Nicolli, H. B., Gutierrez, M., Reyes-Gomez, V. M., … Sracek, O. (2013). Co-occurrence of arsenic and fluoride in groundwater of semi-arid regions in Latin America: Genesis, mobility and remediation. Journal of Hazardous Materials, 262, 960-969. https://doi.org/10.1016/j.jhazmat.2012.08.005
    1. Ali, I., Khan, T. A., & Asim, M. (2012). Removal of arsenate from groundwater by electrocoagulation method. Environmental Science and Pollution Research, 19(5), 1668-1676. https://doi.org/10.1007/s11356-011-0681-3
    1. Arcibar-Orozco, J. A., Josue, D. B., Rios-Hurtado, J. C., & Rangel-Mendez, J. R. (2014). Influence of iron content, surface area and charge distribution in the arsenic removal by activated carbons. Chemical Engineering Journal, 249, 201-209. https://doi.org/10.1016/j.cej.2014.03.096
    1. Aullón Alcaine, A., Bhattacharya, P., Jacks, G., Schulz, C., Bundschuh, J., Thunvik, R., & Mörth, C. M. (2013). Geogenic arsenic and fluoride in shallow aquifers of northeastern La Pampa, Argentina: mobility constraints. In 12th international conference on the biogeochemistry of trace elements (ICOBTE), June (pp. 16-20). USA: Athens.

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