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Book

Anthracycline Medications (Doxorubicin)

Steven Douedi  1 , Michael P. Carson
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan.
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Book

Anthracycline Medications (Doxorubicin)

Steven Douedi et al.
Free Books & Documents

Excerpt

Doxorubicin is an anthracycline class medication used to manage and treat various types of malignancies and tumors. This activity will highlight the mechanism of action, adverse event profile, and other factors, including off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, and relevant interactions.

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Conflict of interest statement

Disclosure: Steven Douedi declares no relevant financial relationships with ineligible companies.

Disclosure: Michael Carson declares no relevant financial relationships with ineligible companies.

References

    1. Meyer M, Seetharam M. First-Line Therapy for Metastatic Soft Tissue Sarcoma. Curr Treat Options Oncol. 2019 Jan 24;20(1):6. - PubMed
    1. Megías-Vericat JE, Martínez-Cuadrón D, Sanz MÁ, Poveda JL, Montesinos P. Daunorubicin and cytarabine for certain types of poor-prognosis acute myeloid leukemia: a systematic literature review. Expert Rev Clin Pharmacol. 2019 Mar;12(3):197-218. - PubMed
    1. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet] National Institute of Diabetes and Digestive and Kidney Diseases; Bethesda (MD): 2021. Sep 10, Cytotoxic Antibiotics.
    1. McGowan JV, Chung R, Maulik A, Piotrowska I, Walker JM, Yellon DM. Anthracycline Chemotherapy and Cardiotoxicity. Cardiovasc Drugs Ther. 2017 Feb;31(1):63-75. - PMC - PubMed
    1. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet] National Institute of Diabetes and Digestive and Kidney Diseases; Bethesda (MD): 2018. Jan 15, Doxorubicin.

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