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Book

Fracture Healing Overview

Jonathon R. Sheen  1 , Ahmed Mabrouk  2 , Vishnu V. Garla  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Fracture Healing Overview

Jonathon R. Sheen et al.
Free Books & Documents

Excerpt

Bone fracture healing: is an intricate and fluent regenerative process that aims at restoring the damaged bone to its pre-injury state and cellular composition. A fracture is a breach in the structural continuity of the bone cortex, with a degree of injury to the surrounding soft tissues. Following the fracture, secondary healing begins, which consists of four steps:

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Conflict of interest statement

Disclosure: Jonathon Sheen declares no relevant financial relationships with ineligible companies.

Disclosure: Ahmed Mabrouk declares no relevant financial relationships with ineligible companies.

Disclosure: Vishnu Garla declares no relevant financial relationships with ineligible companies.

References

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    1. Cheal EJ, Hayes WC, White AA, Perren SM. Stress analysis of compression plate fixation and its effects on long bone remodeling. J Biomech. 1985;18(2):141-50. - PubMed
    1. Lewallen DG, Chao EY, Kasman RA, Kelly PJ. Comparison of the effects of compression plates and external fixators on early bone-healing. J Bone Joint Surg Am. 1984 Sep;66(7):1084-91. - PubMed
    1. Holmström T, Paavolainen P, Slätis P, Karaharju E. Effect of compression on fracture healing. Plate fixation studied in rabbits. Acta Orthop Scand. 1986 Aug;57(4):368-72. - PubMed
    1. Duan ZW, Lu H. Effect of Mechanical Strain on Cells Involved in Fracture Healing. Orthop Surg. 2021 Apr;13(2):369-375. - PMC - PubMed

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