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Editorial
. 2020 Jan;31(1):8-11.
doi: 10.1681/ASN.2019111195. Epub 2019 Dec 16.

Refining Our Understanding of the PLA2R-Antibody Response in Primary Membranous Nephropathy: Looking Forward, Looking Back

Laurence H Beck Jr  1 , David J Salant  2
Affiliations
Editorial

Refining Our Understanding of the PLA2R-Antibody Response in Primary Membranous Nephropathy: Looking Forward, Looking Back

Laurence H Beck Jr et al. J Am Soc Nephrol. 2020 Jan.
No abstract available

Keywords: PLA2R; autoantibody; epitope spreading; membranous nephropathy; phospholipase A2 receptor.

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References

    1. Reinhard L, Zahner G, Menzel S, Koch-Nolte F, Stahl RAK, Hoxha E: Clinical relevance of domain-specific phospholiphase A2 receptor 1 antibody levels in patients with membranous nephropathy. J Am Soc Nephrol 31: 197–207, 2020 - PMC - PubMed
    1. Burbelo L, Joshi M Chaturvedi A Little DJ, Thurlow JS, Waldman M et al. .: Detection of PLA2R autoantibodies before the diagnosis of membranous nephropathy. J Am Soc Nephrol 31: 208–217, 2020 - PMC - PubMed
    1. Dong Y, Cao L, Tang H, Shi X, He Y: Structure of human M-type phospholipase A2 receptor revealed by cryo-electron microscopy. J Mol Biol 429: 3825–3835, 2017 - PubMed
    1. Fresquet M, Jowitt TA, Gummadova J, Collins R, O’Cualain R, McKenzie EA, et al. .: Identification of a major epitope recognized by PLA2R autoantibodies in primary membranous nephropathy. J Am Soc Nephrol 26: 302–313, 2015 - PMC - PubMed
    1. Kao L, Lam V, Waldman M, Glassock RJ, Zhu Q: Identification of the immunodominant epitope region in phospholipase A2 receptor-mediating autoantibody binding in idiopathic membranous nephropathy. J Am Soc Nephrol 26: 291–301, 2015 - PMC - PubMed

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