Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Dec 2;11(4):8248.
doi: 10.4081/pr.2019.8248.

Serological profile of hepatitis B in children after the introduction of its vaccination in Burkina Faso

Makoura Barro  1 , Diane Valea  2 , Saga Alain Ouermi  3 , Sanata Sessouma  2 , Bintou Sanogo  1 , Ibrahim Ad Bafa Ouattara  1 , Abdoul Salam Ouedraogo  4 , Boubacar Nacro  1 , Georges Moyen  5
Affiliations

Serological profile of hepatitis B in children after the introduction of its vaccination in Burkina Faso

Makoura Barro et al. Pediatr Rep. .

Abstract

Viral hepatitis B is a public health issue. We establish the children serological profile of hepatitis B in Bobo-Dioulasso, six years after the introduction of hepatitis B vaccine into the Expanded Program on Immunization. This was a descriptive study of prospective data collection carried out in the Department of Pediatrics and the laboratory of virology of the Centre MURAZ of Bobo-Dioulasso between March 2013 and May 2013. Blood samples were made in search of the following hepatitis B serological markers: anti-HBcAb total, HBsAg, Ac anti-HBs, HBeAg, AcHBs, IgM anti-HBc total. The ELISA method with the Monolisa BIORAD reagents was used. A total of 2015 children were included, 1026 (50, 9%) boys and 989 (49.1%) girls, at an average age of 58±48 months. Out of these 2015 children, 53 (2.6%) were positive to HBsAg including 19 vaccinated cases, one child has received 3 doses plus 1 booster dose of hepatitis B vaccine. We found no statistically significant difference in the carriage of serologic markers of hepatitis B between the unvaccinated group and the vaccinated group. Large-scale studies should be carried out in Burkina Faso to see the real impact of vaccination on the health of our populations.

Keywords: Bobo-Dioulasso; Hepatitis B; children; prevalence; serological profile.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Serological markers according to the number of booster doses of vaccination against hepatitis B.
See this image and copyright information in PMC

References

    1. Spearman CW, Afihene M, Ally R, et al. Hepatitis B in sub-Saharan Africa: strategies to achieve the 2030 elimination targets. Lancet Gastroenterol Hepatol 2017;2:900-9. - PubMed
    1. OMS. Hépatite B. Available from: https://wwwwhoint/fr/news-room/factsheets/detail/hepatitis-b 2015. Consulté le 23 Novembre 2018
    1. Njoya CF, Nkwabong E, Njoya O, et al. Facteurs Associés à la Transmission du Virus de l’Hépatite B de la Mère à l’Enfant: une enquête CAP. Health Sci Dis 2018;19:32-5.
    1. Malam-Abdou B, Brah S, Chefou ME, et al. Le risque infectieux post-transfusionnel: une étude comparative sur la séroprévalence du VIH, des hépatites B et C et de la Syphilis: à propos de 202 patients testés à l’Hôpital National de Niamey (HNN). Health Sci Dis 2016;17:1-4
    1. Loriette M, Birguel J, Damza R, et al. Une expérience de lutte contre l’hépatite B en zone rurale à l’extrême nord du Cameroun. Méd Santé Tropical 2015; 25:422-7. - PubMed

LinkOut - more resources