Paternal sperm DNA mosaicism and recurrence risk of autism in families

Eric M Morrow^{1

2

3

4}

Affiliations

¹ Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA. eric_morrow@brown.edu.
² Developmental Disorders Genetics Research Program, Emma Pendleton Bradley Hospital, East Providence, RI, USA. eric_morrow@brown.edu.
³ Hassenfeld Child Health Innovation Institute, Brown University, Providence, RI, USA. eric_morrow@brown.edu.
⁴ Center for Translational Neuroscience, Robert J. and Nancy D. Carney Institute for Brain Science and Brown Institute for Translational Science, Brown University, Providence, RI, USA. eric_morrow@brown.edu.

Comment

Eric M Morrow. Nat Med. 2020 Jan.

. 2020 Jan;26(1):26-28.

doi: 10.1038/s41591-019-0732-8.

Eric M Morrow^{1

2

3

4}

¹ Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI, USA. eric_morrow@brown.edu.
² Developmental Disorders Genetics Research Program, Emma Pendleton Bradley Hospital, East Providence, RI, USA. eric_morrow@brown.edu.
³ Hassenfeld Child Health Innovation Institute, Brown University, Providence, RI, USA. eric_morrow@brown.edu.
⁴ Center for Translational Neuroscience, Robert J. and Nancy D. Carney Institute for Brain Science and Brown Institute for Translational Science, Brown University, Providence, RI, USA. eric_morrow@brown.edu.

No abstract available

Comment on

Autism risk in offspring can be assessed through quantification of male sperm mosaicism.
Breuss MW, Antaki D, George RD, Kleiber M, James KN, Ball LL, Hong O, Mitra I, Yang X, Wirth SA, Gu J, Garcia CAB, Gujral M, Brandler WM, Musaev D, Nguyen A, McEvoy-Venneri J, Knox R, Sticca E, Botello MCC, Uribe Fenner J, Pérez MC, Arranz M, Moffitt AB, Wang Z, Hervás A, Devinsky O, Gymrek M, Sebat J, Gleeson JG. Breuss MW, et al. Nat Med. 2020 Jan;26(1):143-150. doi: 10.1038/s41591-019-0711-0. Epub 2019 Dec 23. Nat Med. 2020. PMID: 31873310 Free PMC article.

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