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Comment
. 2020 Feb;20(2):71.
doi: 10.1038/s41577-019-0270-0.

bnAbs for HIV: shepherding towards improbable mutations

Alexandra Flemming  1
Affiliations
Comment

bnAbs for HIV: shepherding towards improbable mutations

Alexandra Flemming. Nat Rev Immunol. 2020 Feb.
No abstract available

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Comment on

  • A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
    Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, Hu X, Bernard SM, Georgeson E, Phelps N, Adachi Y, Kubitz M, Landais E, Umotoy J, Robinson A, Briney B, Wilson IA, Burton DR, Ward AB, Crotty S, Batista FD, Schief WR. Steichen JM, et al. Science. 2019 Dec 6;366(6470):eaax4380. doi: 10.1126/science.aax4380. Epub 2019 Oct 31. Science. 2019. PMID: 31672916 Free PMC article.
  • Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
    Saunders KO, Wiehe K, Tian M, Acharya P, Bradley T, Alam SM, Go EP, Scearce R, Sutherland L, Henderson R, Hsu AL, Borgnia MJ, Chen H, Lu X, Wu NR, Watts B, Jiang C, Easterhoff D, Cheng HL, McGovern K, Waddicor P, Chapdelaine-Williams A, Eaton A, Zhang J, Rountree W, Verkoczy L, Tomai M, Lewis MG, Desaire HR, Edwards RJ, Cain DW, Bonsignori M, Montefiori D, Alt FW, Haynes BF. Saunders KO, et al. Science. 2019 Dec 6;366(6470):eaay7199. doi: 10.1126/science.aay7199. Science. 2019. PMID: 31806786 Free PMC article.

References

Original articles
    1. Steichen, J. M. et al. A generalized HIV vaccine design strategy for priming broadly neutralizing antibody responses. Science 366, eaax4380 (2019) - DOI
    1. Saunders, K. O. et al. Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science 366, eaay7199 (2019) - DOI

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