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Randomized Controlled Trial
. 2020 Apr;14(4):335-344.
doi: 10.1111/crj.13138. Epub 2020 Jan 11.

The impact of home-based pulmonary rehabilitation on people with mild chronic obstructive pulmonary disease: A randomised controlled trial

Aroub Lahham  1   2   3 , Christine F McDonald  2   4   5 , Rosemary Moore  2 , Narelle S Cox  1   2   6 , Sarah Rawlings  7 , Amanda Nichols  7 , Athina Liacos  1   7 , Anne E Holland  1   2   6   8
Affiliations
Randomized Controlled Trial

The impact of home-based pulmonary rehabilitation on people with mild chronic obstructive pulmonary disease: A randomised controlled trial

Aroub Lahham et al. Clin Respir J. 2020 Apr.

Abstract

Introduction: People with mild chronic obstructive pulmonary disease (COPD) experience exercise intolerance, dyspnoea and poor quality of life. However, the role of pulmonary rehabilitation (PR) in this group is unclear.

Objectives: This randomised controlled trial aimed to explore the effects of home-based PR in people with mild COPD.

Methods: People with mild COPD (FEV1 /FVC < 70%; FEV1 > 80%predicted) with a smoking history of ≥10 packet years were randomised to either 8 weeks of home-based PR (one home visit and seven once-weekly telephone calls) or standard care (weekly social telephone calls). Six minute walk distance (6MWD), and Modified Medical Research Council Dyspnoea Scale (mMRC) and Chronic Respiratory Disease Questionnaire (CRQ) scores were compared.

Results: A total of 58 participants (34 males, mean age 68 (SD 9) years, FEV1 %predicted 90 (7), 6MWD 496 (105) m) were included with 31 participants randomised to home-based PR. Participants attended an average of 6.8 of the 8 scheduled sessions, ranging from 3 to 8 sessions. Both groups showed improvements in exercise capacity, symptoms and health-related quality of life (HRQoL) over time, however there was no difference in 6MWD at end-intervention (mean difference -3 m, 95% confidence interval (CI) -64 to 58) or 6 months (7 m, 95% CI -59 to 72). At 6 months home-based PR participants were more likely to have clinically important improvements in CRQ emotional function (50% of home PR vs 0% control, P < 0.001) and CRQ total score (45% vs 17%, P = 0.05).

Conclusion: For people with mild COPD, home-based PR did not improve exercise capacity more than standard care. The trial was registered at the Australia New Zealand clinical trial registry (https://www.anzctr.org.au, Trial ID: ACTRN12616000965404).

Keywords: chronic obstructive pulmonary disease; home care services; pulmonary rehabilitation.

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References

REFERENCES

    1. O'Donnell DE, Banzett RB, Carrieri-Kohlman V, et al. Pathophysiology of dyspnea in chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2007;4:145-168.
    1. O'Donnell DE, Gebke KB. Examining the role of activity, exercise, and pharmacology in mild COPD. Postgrad Med. 2014;126:135-145.
    1. Spruit MA, Singh SJ, Garvey C, et al. An official American Thoracic Society/European Respiratory Society Statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med. 2013;188:e13-e64.
    1. The Global Strategy for Diagnosis, Management and Prevention of COPD. Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017. http://goldcopd.org. Accessed June 30, 2017.
    1. Yang I, Brown J, Jenkins S, et al. COPD-X Australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update. Med J Aust. 2017;207:436-442.

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