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. 2019 Dec 30;34(50):e322.
doi: 10.3346/jkms.2019.34.e322.

The Trend in Incidence and Case-fatality of Hospitalized Acute Myocardial Infarction Patients in Korea, 2007 to 2016

Rock Bum Kim #  1 , Hye Sim Kim #  2 , Dae Ryong Kang  3 , Ji Yoo Choi  4 , Nack Cheon Choi  5 , Seokjae Hwang  6 , Jin Yong Hwang  7
Affiliations

The Trend in Incidence and Case-fatality of Hospitalized Acute Myocardial Infarction Patients in Korea, 2007 to 2016

Rock Bum Kim et al. J Korean Med Sci. .

Abstract

Background: The trend in the incidence of hospitalized acute myocardial infarction (AMI) and the difference between regions has not been reported in Korea since 2010. Thus, we aimed to inspect recent trends and regional differences in the incidence of AMI and case-fatality between 2007 and 2016.

Methods: Data from the medical utilization cohort from 2002 to 2016 were analyzed. New incidence of AMI was identified by checking the diagnosis code, duration of admission, type of test, treatment, and medication. Age-standardized incidence rate by gender, age group, and resident region was calculated from 2007 to 2016. Cumulative case-fatality rate was calculated until 3 years.

Results: Age-standardized incidence of hospitalized AMI decreased from 53.6 cases per 100,000 person-years in 2007 to 38.9 cases in 2011. Thereafter, the incidence gradually increased to 43.2 cases in 2016. The trend by gender and age groups was also similar to the total trend. The regional age-standardized incidence was the highest in Daegu (50.3 cases per 100,000 person-years) and the lowest in Sejong (30.2 cases), which were similar to the ischemic heart disease mortality in these regions. The 7-, 30-, and 90-days and 1- and 3-years average case-fatality over 10 years were 3.2%, 6.9%, 9.9%, 14.7%, and 22.4%, respectively.

Conclusion: Although case-fatality continuously decreased from 2007 to 2016, hospitalized AMI incidence decreased from 2007 to 2011 and gradually increased from 2011 to 2016, with marked disparity between regions. Effective preventive strategies to decrease AMI incidence are required to decrease cardiovascular disease mortality in Korea.

Keywords: Acute Myocardial Infarction; Case-Fatality; Incidence Rate; Regional Differences.

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Conflict of interest statement

The authors have no potential conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1. Trend in incidence rate of hospitalized acute myocardial infarction between 2007 and 2016. (A) Age-standardized incidence rate of total population. (B) Crude incidence rate by gender.
Fig. 2
Fig. 2. Average age-standardized incidence rate (per 100,000 persons-year) of hospitalized acute myocardial infarction by 17 regions of Korea during 10 years. The color of the map was represented by gradations from blue to green. The regions with higher incidence rates were painted in blue, while those with lower were painted in green.
SE = Seoul, BS = Busan, DG = Daegu, IC= Incheon, GJ = Gwangju, DJ = Daejeon, US = Ulsan, SJ = Sejong, GG = Gyeonggi, GW = Gangwon, CB = Chungbuk, CN = Chungnam, JB = Jeonbuk, JN = Jeonnam, GB = Gyeongbuk, GN = Gyeongnam, JJ = Jeju.
Fig. 3
Fig. 3. Case-fatality of hospitalized acute myocardial infarction by period from admission between 2007 and 2016. The 1-year or 3-years case-fatality of 2014, 2015, or 2016 patients could not be calculated or may be underestimated. We did not represent this data to avoid confusion and misleading.
See this image and copyright information in PMC

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