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Case Reports
. 2019 Dec 27;19(1):227.
doi: 10.1186/s12876-019-1151-5.

Endoscopic resection of giant gastrointestinal stromal tumor at the esophagogastric junction: a case report

Feng Xue  1 , Wei Wang  1 , Ning Shi  1 , Xing-Bin Ma  1 , Cheng-Xia Liu  2
Affiliations
Case Reports

Endoscopic resection of giant gastrointestinal stromal tumor at the esophagogastric junction: a case report

Feng Xue et al. BMC Gastroenterol. .

Abstract

Background: Gastrointestinal stromal tumors (GISTs) at the esophagogastric junction are rare and its treatment is complicated and challenging. Endoscopic resection has advantages with less complications compared to open and laparoscopic surgery.

Case presentation: We report a 33-year-old male patient who was admitted to our department complaining of abdominal fullness for 20 days. A huge submucosal tumor at the esophagogastric junction was found by upper gastrointestinal endoscopy. We successfully resected the lesion through endoscopic submucosal excavation without complications, which was pathologically confirmed to be a GIST. The patient was discharged 5 days after operation and has been doing well, and there was no recurrence 8 months after the operation.

Conclusion: ESE is possibly an effective and minimally invasive method of giant esophagogastric junction stromal tumor.

Keywords: Case report; Endoscopic submucosal excavation; Esophagogastric junction; Gastrointestinal stromal tumor.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
a, b and c Upper gastrointestinal endoscopy revealing a submucosal tumor at the lesser curvature of the esophagogastric junction. d and e Endoscopic ultrasonography revealed a round, low-echoic mass. f The enhanced computed tomography (CT) scan shows a mass abnormal enhancement, and the lesion is seen on the side of lesser curvature of gastric body (9.5 cm × 6.3 cm) at the esophagogastric junction
Fig. 2
Fig. 2
a Endoscopic features of the submucosal tumor; b, c and d During endoscopic submucosal excavation (ESE); e Endoscopic features after ESE; f Gross features of the specimen from ESE
Fig. 3
Fig. 3
Microscopic examination revealed a spindle-cell neoplasm (a hematoxylin and eosin, × 100), and the tumor cells were positive for CD117 (b × 100) and CD34 (c × 100) and dog-1 (d × 100)
Fig. 4
Fig. 4
Upper gastrointestinal endoscopy (a and b) and abdominal CT examination (c) were performed 4 months after endoscopic treatment
See this image and copyright information in PMC

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