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Case Reports
. 2019 Dec 5:2019:3684282.
doi: 10.1155/2019/3684282. eCollection 2019.

Leiomyomatosis Peritonealis Disseminata with Sarcomatous Transformation: A Rare Case Report and Literature Review

Affiliations
Case Reports

Leiomyomatosis Peritonealis Disseminata with Sarcomatous Transformation: A Rare Case Report and Literature Review

Song Xu et al. Case Rep Obstet Gynecol. .

Abstract

Leiomyomatosis Peritonealis Disseminata (LPD) is an uncommon disease characterized by presence of Multiple Leiomyomas in the abdominal and pelvic cavity. Increasingly, literature supports that LPD is an iatrogenic condition. Malignant transformation of LPD is rarely reported. We hereby report a case of a middle-aged female patient who was diagnosed with malignant sarcomatous degeneration in LPD. Gynecologists may get inspiration from this case report.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
(a) Hypoechoic mass lesion on ultrasound image. (b) Strip-like blood flow signal of the mass on color Doppler flow image.
Figure 2
Figure 2
(a) Multiple lobulated, intermediate intensity lesions in T1W image. (b) Intense enhancement of the lesions following contrast administration in T1W image.
Figure 3
Figure 3
(a) The largest mass on the surface of retroperitoneum. (b) The gross appearance of the larger two lesions.
Figure 4
Figure 4
(a) HE staining of the sample under microscope (magnification: 200x). The arrow refers to atypical spindle cells. (b) The positive result of immunohistochemistry of desmin, which is a specific protein of muscle cells.
Figure 5
Figure 5
(a) An incision is made in the posterior fornix of vagina. (b) The lesion is placed in a fetch bag and the edge of the bag was pulled out through the incision.

References

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    1. Taubert H. D., Wissner S. E., Haskins A. L. Leiomyomatosis peritonealis disseminata; an unusual complication of genital leiomyomata. Obstetrics & Gynecology. 1965:561–574. - PubMed
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