Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jul;108(5):1934-1952.
doi: 10.1002/jbm.b.34535. Epub 2019 Dec 30.

Current status and future outlook of nano-based systems for burn wound management

Morteza Abazari  1 , Azadeh Ghaffari  2   3 , Hamid Rashidzadeh  4 , Safa Momeni Badeleh  2 , Yaser Maleki  5
Affiliations
Review

Current status and future outlook of nano-based systems for burn wound management

Morteza Abazari et al. J Biomed Mater Res B Appl Biomater. 2020 Jul.

Abstract

Wound healing process is a natural and intricate response of the body to its injuries and includes a well-orchestrated sequence of biochemical and cellular phenomena to restore the integrity of skin and injured tissues. Complex nature and associated complications of burn wounds lead to an incomplete and prolonged recovery of these types of wounds. Among different materials and systems which have been used in treating the wounds, nanotechnology driven therapeutic systems showed a great opportunity to improvement and enhancement of the healing process of different type of wounds. The aim of this study is to provide an overview of the recent studies about the various nanotechnology-based management of burn wounds and the future outlook of these systems in this area. Laboratory and animal models for assessing the efficacy of these systems in burn wound management also discussed.

Keywords: burn wound; laboratory and animal models; multicomposites; nanomedicine; nanoparticles; nanotechnology-based systems; scaffolds.

PubMed Disclaimer

References

REFERENCES

    1. Abdullahi, A., Amini-Nik, S., & Jeschke, M. (2014). Animal models in burn research. Cellular and Molecular Life Sciences., 71(17), 3241-3255.
    1. Adhya, A., Bain, J., Ray, O., Hazra, A., Adhikari, S., Dutta, G., … Majumdar, B. K. (2014). Healing of burn wounds by topical treatment: A randomized controlled comparison between silver sulfadiazine and nano-crystalline silver. Journal of Basic and Clinical Pharmacy., 6(1), 29-34.
    1. Alemdaroğlu, C., Degim, Z., Celebi, N., Şengezer, M., Alömeroglu, M., & Nacar, A. (2008). Investigation of epidermal growth factor containing liposome formulation effects on burn wound healing. Journal of Biomedical Materials Research Part A., 85(1), 271-283.
    1. Alemdaroğlu, C., Değim, Z., Çelebi, N., Zor, F., Öztürk, S., & Erdoğan, D. (2006). An investigation on burn wound healing in rats with chitosan gel formulation containing epidermal growth factor. Burns, 32(3), 319-327.
    1. Alvarez, G. S., Hélary, C., Mebert, A. M., Wang, X., Coradin, T., & Desimone, M. F. (2014). Antibiotic-loaded silica nanoparticle-collagen composite hydrogels with prolonged antimicrobial activity for wound infection prevention. Journal of Materials Chemistry B., 2(29), 4660-4670.

LinkOut - more resources