Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Dec;14(4):365-369.
doi: 10.1016/j.jds.2019.04.003. Epub 2019 May 28.

Time trends in the prevalence of diagnosed sialolithiasis from Taiwanese nationwide health insurance dental dataset

Affiliations

Time trends in the prevalence of diagnosed sialolithiasis from Taiwanese nationwide health insurance dental dataset

Yu-Hsun Wang et al. J Dent Sci. 2019 Dec.

Abstract

Background/purpose: Sialolithiasis, the so-called salivary gland stone, is a condition forming salivary calculi within a salivary gland or ducts. Little is known about the epidemiological survey of sialolithiasis in Taiwanese population. In this study, we conducted an age-period-cohort (APC) analysis evaluating the prevalence of sialolithiasis.

Materials and methods: A retrospective study was conducted to analyze the registered database compiled by the Taiwanese National Health Insurance Research Database from 1996 to 2013. The APC analysis was performed to investigate the effects of age, diagnosis period, and birth cohort with sialolithiasis.

Results: We found that the prevalence of sialolithiasis varied from 1.4 (105) to 2.3 (105). The mean age ±standard deviation with sialolithiasis from 1996 to 2013 was 37.7 ± 18.5 and 46.2 ± 18.6 years old, respectively. The prevalence was higher among male than female (RR: 1.10; 95% CI: 1.05-1.15, p < 0.001). The age >65 group had higher risk compared to age <40 group (RR: 2.27; 95% CI: 2.13-2.43, p < 0.001). The relative risk for sialolithiasis demonstrated significant age effect (p < 0.001). The relative risk for sialolithiasis did not show the significant period effect (p = 0.742). The relative risk for sialolithiasis demonstrated significant cohort effect (p = 0.01). The relative risk for sialolithiasis demonstrated significant APC effect (p = 0.002).

Conclusion: Form this nationwide population-based database, the prevalence of sialolithiasis occurs more frequently in male than in female. In addition, the relative risk for sialolithiasis demonstrated the significant APC effects.

Keywords: Age-period-cohort; Nationwide population-based study; Prevalence; Sialolithiasis; Taiwan.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Time trends for the mean age of patients with sialolithiasis from 1996 to 2013.
Figure 2
Figure 2
Age-specific group in the prevalence of sialolithiasis in Taiwan from 1996 to 2013.
Figure 3
Figure 3
Cross–sectional curve from age–period–cohort model (a) age effect (b) period effect (c) birth effect in the rate of sialolithiasis in Taiwan.

Similar articles

Cited by

References

    1. Wang W.C., Chen C.Y., Hsu H.J., Kuo J.H., Lin L.M., Chen Y.K. Sialolithiasis of minor salivary glands: a review of 17 cases. J Dent Sci. 2016;11:152–155. - PMC - PubMed
    1. Lustmann J., Regev E., Melamed Y. Sialolithiasis: a survey on 245 patients and a review of the literature. Int J Oral Maxillofac Surg. 1990;19:135–138. - PubMed
    1. Sigismund P.E., Zenk J., Koch M., Schapher M., Rudes M., Iro H. Nearly 3000 salivary stones: some clinical and epidemiologic aspects. The Laryngoscope. 2015;125:1879–1882. - PubMed
    1. Rauch S., Gorlin R.J. Disease of the salivary glands. In: Gorlin R.J., Goldmann H.M., editors. Oral pathology. Mosby; St Louis, MO: 1970. pp. 997–1003.
    1. Sherman J.A., McGurk M. Lack of correlation between water hardness and salivary calculi in England. Br J Oral Maxillofac Surg. 2000;38:50–53. - PubMed

LinkOut - more resources