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Review
. 2019 Dec 27:10:257.
doi: 10.25259/SNI_417_2019. eCollection 2019.

An update on pediatric surgical epilepsy: Part I

Affiliations
Review

An update on pediatric surgical epilepsy: Part I

Nisha Gadgil et al. Surg Neurol Int. .

Abstract

Epilepsy affects many children worldwide, with drug-resistant epilepsy affecting 20-40% of all children with epilepsy. This carries a significant burden for patients and their families and is strongly correlated with poor cognitive outcomes, depression, anxiety, developmental delay, and impaired activities of daily living. For this reason, we sought to explore the role of pediatric epilepsy surgery and provide an overview of the factors contributing to epilepsy surgery planning and execution. We review the necessary preoperative evaluations, surgical indications, planning considerations, and surgical options to provide a clear pathway in the evaluation and planning of pediatric epilepsy surgery.

Keywords: Drug-resistant epilepsy; Epilepsy surgery; Pediatric.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1:
Figure 1:
Flowchart demonstrating strategies in the surgical management of drug-resistant epilepsy. The goal of epilepsy surgery can range from curative to palliative, with various available techniques to achieve a range of seizure outcome.

References

    1. Asarnow RF, LoPresti C, Guthrie D, Elliott T, Cynn V, Shields WD, et al. Developmental outcomes in children receiving resection surgery for medically intractable infantile spasms. Dev Med Child Neurol. 1997;39:430–40. - PubMed
    1. Benbadis SR, Geller E, Ryvlin P, Schachter S, Wheless J, Doyle W, et al. Putting it all together: Options for intractable epilepsy: An updated algorithm on the use of epilepsy surgery and neurostimulation. Epilepsy Behav. 2018;88S:33–8. Available from: https://www.epilepsybehavior.com/article/S1525-5050(18)30383-4/fulltext [Last accessed on 2018 Sep 23] - PubMed
    1. Berg AT. Identification of pharmacoresistant epilepsy. Neurol Clin. 2009;27:1003–13. - PMC - PubMed
    1. Choi SA, Kim SY, Kim H, Kim WJ, Kim H, Hwang H, et al. Surgical outcome and predictive factors of epilepsy surgery in pediatric isolated focal cortical dysplasia. Epilepsy Res. 2018;139:54–9. - PubMed
    1. Cross JH, Jayakar P, Nordli D, Delalande O, Duchowny M, Wieser HG, et al. Proposed criteria for referral and evaluation of children for epilepsy surgery: Recommendations of the subcommission for pediatric epilepsy surgery. Epilepsia. 2006;47:952–9. - PubMed

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