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Case Reports
. 2019 Dec 22;11(12):e6441.
doi: 10.7759/cureus.6441.

Precocious Puberty Associated with Testicular Hormone-secreting Leydig Cell Tumor

Eid Alagha  1 , Shahd E Kafi  1 , Mohamed Abdelmaksoud Shazly  1 , Abdulmoein Al-Agha  1
Affiliations
Case Reports

Precocious Puberty Associated with Testicular Hormone-secreting Leydig Cell Tumor

Eid Alagha et al. Cureus. .

Abstract

Leydig cell tumors (LCTs) are rare testicular tumors that may be a cause of precocious puberty in males. We present a 5-year-old boy with a five-month history of pubic hair appearance associated with an increase in penile length, scrotal hyperpigmentation, change in body odor, and bone age advanced by two years. His hormonal tests revealed the diagnosis of pseudo precocious puberty. Testicular ultrasound showed a unilateral right testicular enlargement. Surgery was performed to remove the mass. Histopathology confirmed the diagnosis of LCT. This case report highlights the importance of consideration of testicular tumors in boys with precocious puberty.

Keywords: leydig cell tumor; male children; pseudo precocious puberty; testicular tumors.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Pubic hair appearance and genital development (Tanner stage II - arrows)
Figure 2
Figure 2. Bone age imagining reveals two-year advanced age
Figure 3
Figure 3. Testicular ultrasound shows right testicular mass
See this image and copyright information in PMC

References

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