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. 2019 Dec 16:6:2374289519892524.
doi: 10.1177/2374289519892524. eCollection 2019 Jan-Dec.

Educational Case: Group B Streptococcus Meningitis

Affiliations

Educational Case: Group B Streptococcus Meningitis

Tiffany R Miller et al. Acad Pathol. .

Abstract

The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040.1.

Keywords: central nervous system infection; cerebrospinal fluid; group B streptococcus; neonatal meningitis; nervous system; organ system pathology; pathology competencies.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Wright stain (×500) of cerebrospinal fluid specimen illustrating predominance of neutrophils with numerous cocci in pairs.
Figure 2.
Figure 2.
An example of cerebrospinal fluid histology in viral meningitis, where you would see lymphocytosis, which is an abundance of lymphocytes. Reproduced with permission from Dr Peter G. Anderson and the University of Alabama at Birmingham (UAB) Pathology Education Information Resource (PEIR) Digital Library.
Figure 3.
Figure 3.
An example of cerebrospinal fluid histology in fungal meningitis. Seen here is a case of cryptococcus meningitis. Cryptococcus yeast form thick capsules, which is illustrated here, and in some cases, narrow-based budding can be seen. Reproduced with permission from Dr Peter G. Anderson and the University of Alabama at Birmingham (UAB) Pathology Education Information Resource (PEIR) Digital Library.

References

    1. Knollmann-Ritschel BEC, Regula DP, Borowitz MJ, Conran R, Prystowsky MB. Pathology competencies for medical education and educational cases. Acad Pathol. 2017;4 doi:10.1177/2374289517715040. - PMC - PubMed
    1. Nizet V, Jerome KO. Bacterial sepsis and meningitis In: Remington JS, Klein JO, Wilson CB, Nizet V, Maldonado YA, eds. Infectious Diseases of the Fetus and Newborn Infant. 7th ed Philadelphia, PA: W.B. Saunders; 2011:222–275.
    1. Avner JR, Baker MD, Bell LM. Failure of infant observation scales in detecting serious illness in febrile, 4- to 8-week-old infants. Pediatrics. 1990;85:1040–1043. - PubMed
    1. Danis PG, Gardner TD, Norris CM. Aseptic meningitis in the newborn and young infant. Am Fam Physician. 1999;59:2761–2770. - PubMed
    1. Feigin RD, Klein JO, McCracken GH. Report of the Task Force on Diagnosis and Management of Meningitis. Pediatrics. 1986;78:959–982. - PubMed