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Review
. 2021 Jan;36(1):51-63.
doi: 10.1007/s00467-019-04428-y. Epub 2020 Jan 2.

Management of dyslipidemia in pediatric renal transplant recipients

Affiliations
Review

Management of dyslipidemia in pediatric renal transplant recipients

Margret E Bock et al. Pediatr Nephrol. 2021 Jan.

Abstract

Dyslipidemia after kidney transplantation is a common complication that has historically been underappreciated, especially in pediatric recipients. It is also a major modifiable risk factor for cardiovascular disease, a top cause of morbidity and mortality of transplant patients. While most knowledge about post-transplant dyslipidemia has been generated in adults, recommendations and treatment strategies also exist for children and are presented in this review. Awareness of these applicable guidelines and approaches is required, but not sufficient, for the reliable management of dyslipidemia in our patients, and additional needs and opportunities for comprehensive care in this area (e.g., quality improvement) are outlined.

Keywords: Cholesterol; Dyslipidemia; Kidney; Pediatric; Transplant; Triglycerides.

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References

    1. Parekh RS, Carroll CE, Wolfe RA, Port FK (2002) Cardiovascular mortality in children and young adults with end-stage kidney disease. J Pediatr 141:191–197 - PubMed
    1. de Ferranti SD, Steinberger J, Ameduri R, Baker A, Gooding H, Kelly AS, Mietus-Snyder M, Mitsnefes MM, Peterson AL, St-Pierre J, Urbina EM, Zachariah JP, Zaidi AN (2019) Cardiovascular Risk Reduction in High-Risk Pediatric Patients: A Scientific Statement From the American Heart Association. Circulation 139:e603–e634 - PubMed
    1. Kaddourah A, Uthup S, Madueme P, O'Rourke M, Hooper DK, Taylor MD, Colan SD, Jefferies JL, Rao MB, Goebel J (2015) Prevalence and predictors of aortic dilation as a novel cardiovascular complication in children with end-stage renal disease. Clin Nephrol 83:262–271 - PubMed - PMC
    1. Rangaswami J, Mathew RO, Parasuraman R, Tantisattamo E, Lubetzky M, Rao S, Yaqub MS, Birdwell KA, Bennett W, Dalal P, Kapoor R, Lerma EV, Lerman M, McCormick N, Bangalore S, McCullough PA, Dadhania DM (2019) Cardiovascular disease in the kidney transplant recipient: epidemiology, diagnosis and management strategies. Nephrol Dial Transplant 34:760–773 - PubMed
    1. Foster BJ, Dahhou M, Zhang X, Platt RW, Hanley JA (2011) Change in mortality risk over time in young kidney transplant recipients. Am J Transplant 11:2432–2442 - PubMed

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