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Review
. 2020 Apr;185(2):395-398.
doi: 10.1007/s11046-019-00415-x. Epub 2020 Jan 2.

Bloodstream Infection of a Cancer Patient by Cystobasidium minutum: A Case Report and Literature Review

Cicero P Inácio  1   2 , Madi V Diniz  2 , Paulo Sergio R Araújo  3   4 , Marilane S Barros  4 , Melyna C L Andrade  1 , Reginaldo G Lima-Neto  1 , Danielle Patrícia C Macêdo  5 , Rejane P Neves  6
Affiliations
Review

Bloodstream Infection of a Cancer Patient by Cystobasidium minutum: A Case Report and Literature Review

Cicero P Inácio et al. Mycopathologia. 2020 Apr.

Abstract

Emergent fungal infections are uncommon conditions which frequently lead to death. To our knowledge, only a few cases of invasive infection by Cystobasidium minutum (previously known as Rhodotorula minuta) have been reported. Moreover, several factors are responsible for deep site infections, such as catheter-related fungemia. This report describes the first case report of Cystobasidium minutum causing fungemia in Brazil. The pathogens fungemia was demonstrated by catheter and blood culture-proven, and both yeasts were identified by sequences of D1/D2 rDNA region. After the end of antifungal therapy and catheter removal, a second blood culture was found to be negative and the clinical signs and symptoms of the patient improved.

Keywords: Carcinoma; Catheter; Cystobasidium minutum; Fungemia; Rhodotorula minuta.

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