Idiopathic CD4+ T lymphocytopenia: A case report
- PMID: 31898594
- PMCID: PMC7239395
- DOI: 10.4103/jpgm.JPGM_324_19
Idiopathic CD4+ T lymphocytopenia: A case report
Abstract
Idiopathic CD4+ T lymphocytopenia (ICL) is a very rare immunodeficiency syndrome with an unexplained depletion of CD4+ T lymphocytes and no evidence of Human Immunodeficiency Virus (HIV) infection. Here we report a 29-year-old male patient who had severe ulcerative colitis with low level CD4+ count of 254 cells/mm3, and had no evidence of HIV or Human T cell Lymphotrophic virus type I or II infections. He had recurrent Candidiasis infection and his CD4 count was just 53 cells/mm3 after 3 months. The cause for the decline of CD4 T lymphocytes was unknown.
Keywords: CD4 depletion; Candida; lymphocytopenia.
Conflict of interest statement
None
Comment in
-
Idiopathic CD4+T lymphocytopenia: A case report.J Postgrad Med. 2020 Oct-Dec;66(4):226. doi: 10.4103/jpgm.JPGM_718_20. J Postgrad Med. 2020. PMID: 33063701 Free PMC article. No abstract available.
References
-
- Centers for Disease Control. Unexplained CD4+T-lymphocyte depletion in persons without evident HIV infection-United States. MMWR Morb Mortal Wkly Rep. 1992;41:541–5. - PubMed
-
- Brooks JP, Ghaffari G. Idiopathic CD4 lymphocytopenia. Allergy Asthma Proc. 2016;37:501–4. - PubMed
-
- Mukherjee A, Lodha R, Kabra SK. Idiopathic CD4+ T-cell lymphocytopenia. Indian J Pediatr. 2009;76:430–2. - PubMed
-
- Luo L, Li T. Idiopathic CD4 lymphocytopenia and opportunistic infection-An update. FEMS Immunol Med Microbiol. 2008;54:283–9. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Research Materials