Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1977;11(1):11-4.
doi: 10.1007/BF00561781.

Effect in bronchial asthma of a new beta-adrenergic blocking drug atenolol (ICI 66, 082)

N P Boye, J R Vale
Clinical Trial

Effect in bronchial asthma of a new beta-adrenergic blocking drug atenolol (ICI 66, 082)

N P Boye et al. Eur J Clin Pharmacol. 1977.

Abstract

The bronchial effect of intravenous atenolol (ICI 66.082) has been studied in a double-blind cross over trial in 10 patients with pronounced, labile bronchial asthama. A single i.v. dose of atenolol 3 mg. sufficient to cause a fall in heart rate and systolic blood pressure at rest, induced only a slight and clincially almost negligible impairment of ventilatory function. An ordinary therapeutic dose of salbutamol by inhalation far outweighed the bronchial effect of atenolol. The drug appears promising with regard to its cardio-selective properties.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Br Med J. 1975 May 17;2(5967):367-70 - PubMed
    1. Br Med J. 1975 Oct 18;4(5989):133-5 - PubMed
    1. Thorax. 1972 Sep;27(5):572-6 - PubMed
    1. Br Med J. 1974 Nov 23;4(5942):444-7 - PubMed
    1. Br Heart J. 1974 Dec;36(12):1194-1200 - PubMed

Publication types

LinkOut - more resources