Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Dec;35(12):990-992.
doi: 10.1051/medsci/2019195. Epub 2020 Jan 6.

[Natural killer cells: promising targets in cancer therapy]

[Article in French]
Stéphanie Cornen  1 , Pascale André  1 , Laurent Gauthier  1 , Yannis Morel  1 , Éric Vivier  2
Affiliations
Free article
Review

[Natural killer cells: promising targets in cancer therapy]

[Article in French]
Stéphanie Cornen et al. Med Sci (Paris). 2019 Dec.
Free article

Abstract

Title: Les cellules natural killer : des cibles prometteuses dans la thérapie contre le cancer.

Abstract: L’immuno-oncologie est une approche d’immunothérapie novatrice qui change le traitement des cancers en stimulant la capacité du système immunitaire à reconnaître et éliminer les cellules tumorales. Cette approche a pour but de mettre en place une immuno-surveillance anti-tumorale durable chez des patients pour lesquels les thérapies conventionnelles ont échoué.

PubMed Disclaimer

References

    1. Sharma P, Allison JP. Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential. Cell 2015 ; 161: 205–214.
    1. Chiossone L, Dumas PY, Vienne M, et al. Natural killer cells and other innate lymphoid cells in cancer. Nat Rev Immunol 2018 ; 18: 671–688.
    1. André P, Denis C, Soulas C, et al. Anti-NKG2A mAb is a checkpoint inhibitor that promotes anti-tumor immunity by unleashing both T and NK cells. Cell 2018: 1–13.
    1. Hoffman LM, Gore L. Blinatumomab, a bi-specific anti-CD19/CD3 BiTE(®) antibody for the treatment of acute lymphoblastic leukemia: perspectives and current pediatric applications. Front Oncol 2014 ; 4: 63.
    1. June CH, O’Connor RS, Kawalekar OU, et al. CAR T cell immunotherapy for human cancer. Science 2018 ; 359: 1361–1365.

MeSH terms

LinkOut - more resources