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Review
. 2019 Dec;35(12):1066-1071.
doi: 10.1051/medsci/2019207. Epub 2020 Jan 6.

[Antibodies, tools of choice for fluorescence-guided surgery]

[Article in French]
Affiliations
Free article
Review

[Antibodies, tools of choice for fluorescence-guided surgery]

[Article in French]
André Pèlegrin et al. Med Sci (Paris). 2019 Dec.
Free article

Abstract

Fluorescence-guided surgery has been developing in clinics for several years. While the use of non-targeted dyes may be useful in certain diseases, specific contrast agents are essential in oncology. As shown in the latest clinical studies, monoclonal antibodies have all the characteristics to play a major role in this field of medical imaging, provided the antigenic target is relevant.

Title: Les anticorps, outils de choix pour la chirurgie guidée par fluorescence.

Abstract: La chirurgie guidée par fluorescence se développe en clinique depuis plusieurs années. Si l’utilisation de colorants non ciblés peut être utile dans certaines pathologies, des agents de contraste spécifiques sont indispensables en oncologie. Comme le montrent les dernières études cliniques, les anticorps monoclonaux ont toutes les caractéristiques pour jouer un rôle majeur dans ce domaine d’imagerie médicale, à condition que la cible antigénique soit pertinente.

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